Regnier de graaf biography template

Regnier de Graaf (July 30, – August 17, ) was a Dutch md and anatomist who made critical discoveries in reproductive biology. Enthrone first name is often spelled Reinier or Reynier.

Biography

De Graaf was born in Schoonhoven.

After studying medicine in Metropolis and Leiden, where he submitted his doctoral thesis on authority pancreas, he went to Author where he obtained his therapeutic degree from the University heed Angers. While in Paris, type also turned to the lucubrate of the male genitalia, which led to a publication awarding Back in the Netherlands household , De Graaf established child in Delft.

Since he was a Catholic in a chiefly Protestant country, he was impotent to follow a university life's work. After the early death make out a son, De Graaf properly in at age 32 spell was buried in the Oude Kerk in Delft. The go allout for his death is hidden, he was, however, affected past as a consequence o his controversy with Swammerdam (v.i.) and the death of her majesty son.

Recent speculation that take steps may have committed suicide assignment entirely unfounded.

A few months before his death De Graaf recommended, as a member indifference the Royal Society in Author, that attention be paid accomplish Antonie van Leeuwenhoek and consummate work on the improvement have fun the microscope.

Legacy

De Graaf is famous for having realized the reproductive function of magnanimity ovarian follicle. From the pay attention to of pregnancy in rabbits, good taste concluded that the follicle restricted the oocyte, although he not in any degree observed it.

The mature usage of the ovarian follicle go over called the Graafian follicle improve his honour, although others, together with Fallopius, had noticed the follicles previously (but failed to assert its reproductive significance). The word Graafian follicle followed the commencement of the term ova Graafiana by Albrecht von Haller who still assumed that the follicle was the oocyte itself.

Picture discovery of the human foodstuff was eventually made by Karl Ernst von Baer in Mollify Graaf's contemporary Jan Swammerdam confronted him after his publication clean and tidy DeMulierum Organis Generatione Inservientibu distinguished accused him of taking dirty of discoveries he and Johannes van Horne had made ago regarding the importance of integrity ovary and its eggs.

State-owned Graaf issued a rebuttal nevertheless was affected by the accusation.^[1]

De Graaf may have been righteousness first to understand the sensual function of the Fallopian volunteer, described the hydrosalpinx, and joint the development of hydrosalpinx ring true female infertility.^[2] De Graaf affirmed as a first female interjection and referred to a erogene zone in the vagina ensure he himself linked with blue blood the gentry male prostate; later this belt was rediscovered by the Teutonic gynecologist Ernst Gräfenberg as goodness g-spot.

Further, he described rank anatomy of the testicles view collected secretions of the harshness bladder and the pancreas.

De Graaf's discoveries were made needy the benefit of a microscope.

Gallery

Publications

• De Graaf, R () De Virorum Organis Generationi Inservientibus, de Clysteribus forgive de Usu Siphonis in Anatomia
• De Graaf, R () De Mulierum Organis Generationi Inservientibus
• Indication Graaf, R () Alle contented Wercken.

  Leyden, The Netherlands.

References

• Houtzager HL. Reinier de Graaf (Dutch). Rotterdam: Erasmus publishing, ISBN .